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Zoster (Herpes Zoster / Shingles)

What is Zoster (Herpes Zoster / Shingles)?
Zoster, also known as Herpes Zoster or Shingles, is a viral infection caused by the reactivation of the varicella-zoster virus (the same virus that causes chickenpox). After an initial chickenpox infection, the virus remains dormant in nerve cells and can reactivate years later, causing a painful rash and nerve inflammation.

What Causes Zoster (Herpes Zoster / Shingles)?

  • Reactivation of Varicella-Zoster Virus – The dormant virus in nerve tissue becomes active again, often triggered by weakened immunity.
  • Age – Most common in older adults, especially those over 50 years.
  • Immunosuppression – Conditions or treatments that weaken the immune system can increase risk.
  • Stress and Illness – Physical or emotional stress and certain illnesses can trigger reactivation.

What Are the Symptoms of Zoster (Herpes Zoster / Shingles)?
Symptoms typically begin with:

  • Pain, burning, or tingling in a specific area on one side of the body or face
  • A red rash that develops into fluid-filled blisters
  • Blisters that crust over in 7-10 days

Other symptoms may include:

  • Fever
  • Headache
  • Fatigue
  • Sensitivity to touch

How is Zoster (Herpes Zoster / Shingles) Diagnosed?

  • Clinical Evaluation – Diagnosis is usually made based on characteristic rash and symptoms.
  • Laboratory Tests – PCR or direct fluorescent antibody tests can confirm the virus in unclear cases.

How is Zoster (Herpes Zoster / Shingles) Treated?
Treatment aims to reduce pain, speed healing, and prevent complications:

  • Antiviral Medications – Such as acyclovir, valacyclovir, or famciclovir, ideally started within 72 hours of rash onset.
  • Pain Management – Analgesics, including NSAIDs, acetaminophen, or stronger pain medications if needed.
  • Topical Treatments – To soothe skin and reduce discomfort.
  • Corticosteroids – Sometimes used to reduce inflammation.

Prognosis of Zoster (Herpes Zoster / Shingles)
Most people recover fully, but some may develop complications such as postherpetic neuralgia, a condition causing persistent nerve pain after the rash heals.

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