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What Causes Sudden Weight Loss?

Sudden or unexplained weight loss is when you lose a significant amount of weight without trying through diet or exercise. It can be a warning sign of an underlying health condition and should not be ignored.

Common Causes of Sudden Weight Loss

1. Hyperthyroidism
An overactive thyroid speeds up metabolism, leading to weight loss despite normal or increased appetite.

2. Diabetes
High blood sugar levels can cause your body to use muscle and fat for energy, resulting in unintentional weight loss.

3. Digestive Disorders
Conditions like Crohn’s disease, celiac disease, or ulcers can interfere with nutrient absorption and lead to weight loss.

4. Cancer
Many types of cancer cause rapid weight loss, especially in the later stages.

5. Infections
Chronic infections such as tuberculosis, HIV/AIDS, or parasites can cause weight loss along with fatigue and fever.

6. Mental Health Issues
Depression, anxiety, and eating disorders like anorexia nervosa can reduce appetite and cause significant weight loss.

7. Medications and Treatments
Certain drugs, chemotherapy, or treatments can affect appetite or nutrient absorption.

8. Heart Failure or Chronic Illness
Severe health conditions like heart failure or chronic kidney or liver disease may reduce appetite and cause weight loss over time.

9. Malnutrition or Poor Diet
Not eating enough or having a diet lacking in key nutrients can cause gradual weight loss.

When to See a Doctor

  • You lose more than 5% of your body weight in 6 to 12 months without trying
  • You experience symptoms like fatigue, fever, digestive problems, or mood changes
  • You have a known health condition and notice unintentional weight loss

What to Expect During Evaluation

Your doctor may:

  • Ask about your diet, lifestyle, and medical history
  • Perform a physical exam
  • Order blood tests, imaging, or stool tests
  • Refer you to a specialist if needed

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